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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NPHP3
All Species:
20.61
Human Site:
Y349
Identified Species:
50.37
UniProt:
Q7Z494
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q7Z494
NP_694972.3
1330
150864
Y349
P
I
D
V
E
N
Q
Y
L
T
V
R
K
W
E
Chimpanzee
Pan troglodytes
XP_516758
2073
234018
Y362
P
I
D
V
E
N
Q
Y
L
T
V
R
K
W
E
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_863943
2040
230770
Y329
P
I
D
I
E
N
K
Y
L
A
V
R
K
W
E
Cat
Felis silvestris
Mouse
Mus musculus
Q7TNH6
1324
150168
Y345
P
L
D
V
E
N
Q
Y
L
T
V
R
K
W
E
Rat
Rattus norvegicus
XP_343462
1325
150597
Y345
P
I
D
V
E
N
Q
Y
L
T
L
R
K
W
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514031
1275
145541
L334
N
P
E
G
K
P
R
L
I
Y
R
R
L
E
D
Chicken
Gallus gallus
XP_418790
1315
149161
S334
P
A
E
N
E
N
H
S
K
E
V
R
K
W
E
Frog
Xenopus laevis
Q6AZT7
1300
148301
H326
P
E
E
C
E
S
Q
H
F
A
V
R
K
W
E
Zebra Danio
Brachydanio rerio
XP_691073
1303
148244
F326
P
E
E
K
A
A
V
F
A
A
E
R
R
R
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001203493
1012
113472
E103
E
N
R
R
L
R
A
E
L
Q
A
L
Q
K
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
61.7
N.A.
61.5
N.A.
88.8
87.9
N.A.
78
83.9
76.9
69.9
N.A.
N.A.
N.A.
N.A.
30.9
Protein Similarity:
100
62.4
N.A.
63
N.A.
93.3
93.3
N.A.
86.2
90.7
86.5
82.9
N.A.
N.A.
N.A.
N.A.
49.1
P-Site Identity:
100
100
N.A.
80
N.A.
93.3
93.3
N.A.
6.6
53.3
53.3
20
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
100
N.A.
93.3
N.A.
100
100
N.A.
40
60
73.3
40
N.A.
N.A.
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
0
10
10
10
0
10
30
10
0
0
0
0
% A
% Cys:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
50
0
0
0
0
0
0
0
0
0
0
0
10
% D
% Glu:
10
20
40
0
70
0
0
10
0
10
10
0
0
10
80
% E
% Phe:
0
0
0
0
0
0
0
10
10
0
0
0
0
0
0
% F
% Gly:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
10
10
0
0
0
0
0
0
0
% H
% Ile:
0
40
0
10
0
0
0
0
10
0
0
0
0
0
0
% I
% Lys:
0
0
0
10
10
0
10
0
10
0
0
0
70
10
0
% K
% Leu:
0
10
0
0
10
0
0
10
60
0
10
10
10
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
10
10
0
10
0
60
0
0
0
0
0
0
0
0
0
% N
% Pro:
80
10
0
0
0
10
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
50
0
0
10
0
0
10
0
0
% Q
% Arg:
0
0
10
10
0
10
10
0
0
0
10
90
10
10
0
% R
% Ser:
0
0
0
0
0
10
0
10
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
40
0
0
0
0
10
% T
% Val:
0
0
0
40
0
0
10
0
0
0
60
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
70
0
% W
% Tyr:
0
0
0
0
0
0
0
50
0
10
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _